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KMID : 0438520060130010184
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Journal of the Korean Society of Neonatology
2006 Volume.13 No. 1 p.184 ~ p.189
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Successful Treatment of Candida albicans Endocarditis with Liposomal Amphotericin B (AmBisome) in a Very Low Birth Weight Infant
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Park Hong-Kyu
Lee Hae-Ran
Kim Young-Ho
Kim Me-Jin
Jung Ji-Ah
Yang Seung
Hwang Il-Tae
Sung Nam-Ju
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Abstract
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Candida albicans endocarditis is an uncommon manifestation of systemic candidiasis in newborn infants who require intensive care and develops mostly in patients with congenital heart disease; open heart surgery is the majority of predisposing factor. Improvement of techniques managing premature infants leads to increased survival rates, which give much more chances to develop fungal infections and its complications. We report a case of very low birth weight infant who had candidemia and Candida endocarditis, who was successfully treated with AmBisome® because of no response to conventional amphotericin B therapy. (J Korean Soc Neonatol 2006;13:184-188)
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KEYWORD
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Neonate, Candida albicans, Endocarditis, Liposomal Amphotericin B
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